Disposition Index Calculator

Formula

To calculate the Disposition Index:

\[ DI = \frac{I \cdot G}{F - B} \]

Where:

\(DI\) is the Disposition Index
\(I\) is the Insulin Sensitivity
\(G\) is the Glucose Effectiveness
\(F\) is the Fasting Plasma Glucose
\(B\) is the Basal Insulin

What is a Disposition Index?

A Disposition Index is a clinical metric used in diabetes research to assess the body’s ability to regulate blood glucose levels. It is calculated by multiplying the body’s insulin sensitivity by its insulin response. A lower Disposition Index indicates a higher risk of developing type 2 diabetes, as it suggests that the body is not properly responding to insulin and/or is not producing enough insulin to maintain normal blood glucose levels.

Example Calculation 1

Let's assume the following values:

Insulin Sensitivity (\(I\)) = 2
Glucose Effectiveness (\(G\)) = 3
Fasting Plasma Glucose (\(F\)) = 100
Basal Insulin (\(B\)) = 10

Using the formula:

\[ DI = \frac{2 \cdot 3}{100 - 10} = \frac{6}{90} = 0.067 \]

The Disposition Index is 0.067.

Example Calculation 2

Let's assume the following values:

Insulin Sensitivity (\(I\)) = 4
Glucose Effectiveness (\(G\)) = 5
Fasting Plasma Glucose (\(F\)) = 120
Basal Insulin (\(B\)) = 20

Using the formula:

\[ DI = \frac{4 \cdot 5}{120 - 20} = \frac{20}{100} = 0.2 \]

The Disposition Index is 0.2.