The formula to calculate the Apparent Volume of Distribution (V_d) is:
\[ V_d = \frac{D}{C} \]
Where:
The apparent volume of distribution (V_d) is a pharmacokinetic parameter that quantifies the distribution of a drug within the body relative to the concentration of the drug in the blood or plasma. It is an important parameter that helps in understanding how a drug disperses into body tissues and fluids. A larger volume of distribution indicates that the drug extensively distributes into body tissues, while a smaller volume suggests that the drug remains largely within the blood plasma.
Consider an example where:
Using the formula to calculate the Apparent Volume of Distribution:
\[ V_d = \frac{500}{10} = 50 \text{ L} \]
This means that the apparent volume of distribution for this example is 50 L.
