The allele frequency is calculated using the Hardy-Weinberg equation:
\[ p^2 + 2pq + q^2 = 1 \]
Where:
\( p^2 \) = Frequency of people with two healthy alleles
\( 2pq \) = Frequency of carriers (one healthy and one impaired allele)
\( q^2 \) = Frequency of people with two impaired alleles (the disease)
